Findings from this review are useful in addressing mechanisms involved in key metabolic areas and a wrap up on different aspects of each study. Additionally, within this review we aim to provide an updated summery of beetroot consumption and its ultimate effects on blood glucose, blood pressure and microbiome levels, vascular and renal function and therefore, incidence of metabolic syndrome. This comprehensive review provided a detailed, reliable proof on the treatment of the elevated renal parameters including renal resistive index and arterial stiffness with beetroot and its components. Also, the hypotensive and hypoglycemic effect of beetroot juice consumption had not been firmly attributed to one and major responsible mechanism such analytic vision was seen across microbial and renal studies as well. The overall results were ultimately found to be mostly inconsistent. So far, various interventional studies from selective literature have explored and addressed the implications of beetroot and its byproducts on systolic and diastolic blood pressures, vascular and endothelial function, insulin and glucose responses within the glycemic homeostatic context, and the abundance of microbiome. It is notable that most recent studies on beetroot supplementation, especially those addressing its hypotensive and ergogenic properties, emphasized the critical role of inorganic NO 3 on the clinical effect of this vegetable and its byproducts. Therefore, beetroot is currently being applied as a functional ingredient in the development of various meals. As a rich and nutritious source, it is believed to hold health-promotional characteristics, anti-oxidant and anti-inflammatory effects, anti-carcinogenic and anti-diabetic activities and hepato-protective, hypotensive and wound healing properties. vulgaris conditiva, includes a variety of edible taproots originated from the Middle East, which has been spreading worldwide, from the Americas to Europe and Asia. Despite the inconsistencies in the set of results from the reviewed studies, there is no doubt that further contributing factors must be investigated more deeply in future studies.īeetroot, an annual or biennial cultivated form of Beta vulgaris subsp. Within this context, this review aims to provide a comprehensive overview on the therapeutic applications of beetroot juice in metabolic disorders and theirs underlying mechanisms. The significant blood pressure lowering effect has been seen among normotensive subjects, which tend to be more considerable among hypertensive individuals and progressive among overweight adults. Similarly, it is shown that the persistent consumption of beetroot juice effectively postpones the postprandial glycemic response and decreases the blood glucose peak. Also, some studies have suggested a reno-protective property of beetroot juice that is associated with the reduction of mortality rate and favorable changes in kidney’s functional parameters among patients with renal disorders. The secondary outcome and physiological response of microbiome abundance modulation included the non- significant fluctuation of systolic and diastolic blood pressures. Chronic and acute beetroot juice supplementation, as a cost-effective strategy, is proposed to hold promises in controlling diabetes and insulin hemostasis, blood pressure and vascular function, renal health and the possible effect on microbiome abundance. Red beetroot ( Beta vulgaris), as a naturally occurring root vegetable and a rich source of phytochemicals and bioactive compounds, is known for its beneficial roles in the improvement of several clinical and pathologic outcome.
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